Is there a pin-compatible replacement for 74HC4051PW,118?

No fully pin-compatible, drop-in replacement has been confirmed. While some alternatives share the same package, they have different voltage ratings and their pinouts must be verified against the 74HC4051PW,118 datasheet before use.

What risks should I check before replacing 74HC4051PW,118?

The most critical risk is the supply voltage. The 74HC4051PW,118 supports up to 10V, while many alternatives are limited to 5.5V. Also, verify the pinout, on-state resistance, and switching times to ensure compatibility.

74HC4051PW,118 Alternatives, Datasheet & Cross Reference | Nexperia USA Inc.

The Nexperia 74HC4051PW,118 is a popular 8-channel analog multiplexer. While no direct drop-in replacements are identified, several functional alternatives exist but require careful review of supply voltage and pinout.

AI replacement insight

Electrical riskhigh

Most alternatives have a max voltage of 5.5V, far below the target's 10V.

Package riskmedium

While package matches, pinout must be verified for each alternative.

Firmware risklow

As a simple analog switch, no firmware changes are expected.

Can it be replaced directly?

No direct, pin-compatible replacement for the 74HC4051PW,118 has been identified that matches its full 2V to 10V supply voltage range.

Best replacement path

Use a functional alternative like ADG708BRUZ-REEL7, but only if the system supply voltage is within its 1.8V to 5.5V range. Pinout verification is mandatory.

Main risk

The primary risk is electrical overstress, as potential alternatives have a much lower maximum supply voltage (typically 5.5V vs. 10V).

Recommended alternatives

Functional 8:1 mux in the same package, but with a limited voltage range (2.5V-5.5V) and unconfirmed dual supply support.

View details

Alternative comparison matrix

Feature / factor	74HC4051PW,118	ADG708BRUZ-REEL7	RS2251XTSS16	Compatibility / risk
Package	16-TSSOP	16-TSSOP	16-TSSOP	16-TSSOP — Package matches.; RS2251XTSS16: Package matches.
Voltage	2V ~ 10V	1.8V ~ 5.5V	missing	1.8V ~ 5.5V / missing — Candidate has a much narrower and lower supply voltage range.; RS2251XTSS16: Dual supply support is not specified, while target supports it.
Resistance	120 Ohm	4.5 Ohm	58 Ohm	4.5 Ohm / 58 Ohm — Significantly lower on-state resistance is an upgrade.; RS2251XTSS16: Lower on-state resistance is an upgrade.
Pinout	Standard 4051	unknown	unknown	unknown — Pinout must be verified from datasheet.; RS2251XTSS16: Pinout must be verified from datasheet.
Temperature	-40°C ~ 125°C	-40°C ~ 125°C	-	-40°C ~ 125°C — Operating temperature range matches.

Application & sourcing insights

Questions & answers

The best alternative depends on your circuit's supply voltage. If it's 5.5V or less, parts like Analog Devices' ADG708BRUZ-REEL7 offer better performance (lower resistance) but require pinout verification.