
Chipanalog
CA-IS3722LS is a same-family functional option with pinout caveats.
CA-IS3721LS is a high-speed 2-channel digital isolator. Alternatives require pinout, channel direction, and fail-safe review.
Fail-safe and direction matter.
Kept parts are SOIC-8.
No protocol firmware implied.
Stock not provided.
No pin-compatible replacement is verified from the provided evidence.
Start with CA-IS3722LS for same-family review, then verify pin table.
Pinout and channel direction can block a board-level swap.

Chipanalog
CA-IS3722LS is a same-family functional option with pinout caveats.
| Feature / factor | CA-IS3721LS | CA-IS3722LS | NSI8120N0 | Alt 3 | Compatibility / risk |
|---|---|---|---|---|---|
| Package | SOIC-8 | SOIC-8 | SOIC-8 | SOIC-8 — same package name; NSI8120N0: same package name | |
| Pinout | CA-IS3721LS | CA-IS3722LS | unknown | CA-IS3722LS / unknown — web says pin placement differs; NSI8120N0: no pin table evidence | |
| Voltage | 3.75kVrms, 2.5-5.5V | 3.75kVrms, 2.5-5.5V | 3.75kVrms, 2.5-5.5V | 3.75kVrms, 2.5-5.5V — ratings match; NSI8120N0: ES ratings match | |
| Interface | 2ch 150Mbps 1F/1R low | 2ch 150Mbps 1F/1R low | 2ch 150Mbps low | 2ch 150Mbps 1F/1R low / 2ch 150Mbps low — ES match; NSI8120N0: direction missing | |
| Temperature | missing | -40 to 125C | -40 to 125C | -40 to 125C — target temp absent; NSI8120N0: target temp absent |
CA-IS3722LS is the closest provided option, but it needs pinout review.