
Prisemi
A strong pin-compatible candidate with a higher power rating, but different capacitance.
ESD5451X-ES is a 5V bi-directional TVS diode in a DFN1006-2L package, offering robust ±30kV ESD protection. Finding a substitute requires matching the package, voltage, and directionality, while carefully checking power ratings and capacitance.
Capacitance and clamping voltage vary between candidates and require verification.
DFN1006-2L is a common package with a standard footprint.
Multiple vendors offer parts in this package and voltage rating.
Direct replacement for ESD5451X-ES should use only Datasheet verified or Strong match candidates; many approved options still require engineering review.
The most promising path is Prisemi's PESDNC2FD5VBH, which offers an upgrade in power rating but requires checking for capacitance impact.
The main risk is ensuring the substitute's capacitance does not negatively impact signal integrity, and that its clamping voltage and power rating provide adequate protection.

Prisemi
A strong pin-compatible candidate with a higher power rating, but different capacitance.
| Feature / factor | ESD5451X-ES | PESDNC2FD5VBH | UAD8C05L01-ES | SELC2F5V1B | Compatibility / risk |
|---|---|---|---|---|---|
| Package | DFN1006-2L | DFN1006-2L | DFN1006-2L | DFN1006-2L | DFN1006-2L — Form factor matches.; UAD8C05L01-ES: Form factor matches.; SELC2F5V1B: Form factor matches.; WE05DF-BH: Form factor matches. |
| Voltage | 5.0V | 5.0V | 5.0V | - | 5.0V — Working voltage matches.; UAD8C05L01-ES: Working voltage matches.; WE05DF-BH: Working voltage matches. |
| Power | 96W | 100W | 80W | 80W | 100W / 80W / 77W — Slightly higher power rating.; UAD8C05L01-ES: Lower power rating offers less protection.; SELC2F5V1B: Lower power rating offers less protection.; WE05DF-BH: Lower power rating offers less protection. |
| Capacitance | 15pF | 35pF | 0.3pF | 0.3pF | 35pF / 0.3pF — Higher capacitance may affect high-speed signals.; UAD8C05L01-ES: Significantly lower capacitance may be beneficial for high-speed lines but is a parametric difference.; SELC2F5V1B: Significantly lower capacitance. |
| Breakdown Voltage | 5.6V | 6.4V | - | - | 6.4V — Slightly higher breakdown voltage. |
| Clamping Voltage | 10V @ 1A | - | - | 12V @ 1A | 12V @ 1A — Higher clamping voltage reduces protection level. |
| Polarity Or Type | Bi-directional | - | - | - | Unknown — Directionality must be verified from datasheet. |
Verified drop-in options for ESD5451X-ES are limited in the current batch. Review candidates marked Strong match or Datasheet verified, and validate package, pinout, and electrical limits before committing a BOM change.