
Broadcom/AVAGO
A strong alternative in the same package and series with matching key electrical parameters.
Finding a substitute for the HCPL-M601-500E involves matching its 10 Mbd data rate, open-collector output, and SO-5 package. Fortunately, a strong pin-compatible option exists within the same product family.
Both parts use the same SO-5 package, ensuring physical compatibility.
Key static and dynamic parameters like data rate and output type match. Minor differences in propagation delay should be verified.
Both parts are from the same manufacturer, simplifying supply chain management.
Direct replacement for HCPL-M601-500E should use only Datasheet verified or Strong match candidates; many approved options still require engineering review.
The Broadcom HCPL-M600-500E is the most promising replacement, sharing the same series, package, and key electrical specifications. A datasheet review to confirm pinout and propagation delays is the final step.
The primary risk is a subtle difference in dynamic characteristics like propagation delay, skew, or common-mode rejection (CMR) that could affect timing in high-speed circuits.

Broadcom/AVAGO
A strong alternative in the same package and series with matching key electrical parameters.
| Feature / factor | HCPL-M601-500E | HCPL-M600-500E | HCPL-M453-500E | Alt 3 | Compatibility / risk |
|---|---|---|---|---|---|
| Package | SO-5 | SO-5 | SO-5 | SO-5 — Package matches.; HCPL-M453-500E: Package matches. | |
| Pinout | 5 | 5 | - | 5 — Pin count matches. Pinout is likely identical but requires datasheet verification. | |
| Data Rate | 10 Mbd | 10 Mbd | 1 Mb/s | 10 Mbd / 1 Mb/s — Data rate matches.; HCPL-M453-500E: Significantly lower data rate. | |
| Output Type | Open Collector | Open Collector | - | Open Collector — Output type matches. | |
| Temperature | -40°C to 85°C | -40°C to 85°C | 0°C to 70°C | -40°C to 85°C / 0°C to 70°C — Operating temperature range matches.; HCPL-M453-500E: Narrower commercial temperature range. | |
| Current | 5 mA | - | 16 mA | 16 mA — Higher forward current requirement. |
Verified drop-in options for HCPL-M601-500E are limited in the current batch. Review candidates marked Strong match or Datasheet verified, and validate package, pinout, and electrical limits before committing a BOM change.