
Texas Instruments
Strong functional and parametric match; likely pin-compatible but requires pinout verification.
Find replacements for the MAX3221IPWR, a single-channel RS-232 transceiver in a TSSOP-16 package. Alternatives may require pinout or temperature range verification.
TSSOP-16 is a standard package with good availability.
Some alternatives have a narrower temperature range. Pinout must be verified.
Direct replacement for MAX3221IPWR should use only Datasheet verified or Strong match candidates; many approved options still require engineering review.
TRS3221EIPWR offers the most direct replacement path, matching all critical parameters.
The main risk is ensuring pin-for-pin compatibility and that the substitute's temperature range meets application requirements.

Texas Instruments
Strong functional and parametric match; likely pin-compatible but requires pinout verification.
| Feature / factor | MAX3221IPWR | TRS3221EIPWR | MAX3221ECPWR | Alt 3 | Compatibility / risk |
|---|---|---|---|---|---|
| Package | TSSOP-16 | TSSOP-16 | TSSOP-16 | TSSOP-16 — Package type matches.; MAX3221ECPWR: Package type matches. | |
| Interface | 1/1 | 1/1 | 1/1 | 1/1 — Number of drivers/receivers matches.; MAX3221ECPWR: Number of drivers/receivers matches. | |
| Voltage | 3V to 5.5V | 3V to 5.5V | 3V to 5.5V | 3V to 5.5V — Supply voltage range matches.; MAX3221ECPWR: Supply voltage range matches. | |
| Temperature | -40°C to 85°C | -40°C to 85°C | 0°C to 70°C | -40°C to 85°C / 0°C to 70°C — Industrial temperature range matches.; MAX3221ECPWR: Commercial temp range is narrower than target's industrial range. | |
| Current | 1µA | 1µA | - | 1µA — Low standby current with auto-powerdown matches. |
Verified drop-in options for MAX3221IPWR are limited in the current batch. Review candidates marked Strong match or Datasheet verified, and validate package, pinout, and electrical limits before committing a BOM change.